Young S, Murray K, Mwesigwa J, Natureeba P, Osterbauer B, Achan J, Arinaitwe E, Clark T, Ades V, Plenty A, Charlebois E, Ruel T, Kamya M, Havlir D, Cohan D. Maternal nutritional status predicts adverse birth outcomes among HIV-infected Rural Ugandan women receiving combination antiretroviral therapy. PLOS ONE. 2012; 7(8):E41934. PMC3413694.
Morgan MC, Ruel TD, Kumar GS, Sabnis AJ, Kaiser SV. Predictors of Neonatal Sepsis in Rural Karnataka, India. Asian Journal of Clinical Pediatrics and Neonatology. 2013 (1):6-10.
Jenster M, Bonifacio S, Ruel T, Rogers E, Yun Tam EW, Partridge J, Barkovich J, Ferriero D, and Glass H. Maternal or neonatal infection: association with neonatal encephalopathy outcomes. Pediatric Research. 2014; 76(1):93-9.
Young SL, Plenty AH, Luwedde FA, Natamba BK, Natureeba P, Achan J, Mwesigwa J, Ruel TD, Ades V, Osterbauer B, Clark TD, Dorsey G, Charlebois ED, Kamya M, Havlir DV, Cohan DL. Household Food Insecurity, Maternal Nutritional Status, and Infant Feeding Practices Among HIV-infected Ugandan Women Receiving Combination Antiretroviral Therapy. Maternal Child Health Journal. 2014. March.
Gandhi M, Mwesigwa J, Aweeka F, Plenty A, Charlebois E, Ruel TD, Huang Y, Clark T, Ades V, Natureeba P, Luwedde FA, Achan J, Kamya MR, Havlir DV, Cohan D; Prevention of Malaria and HIV disease in Tororo (PROMOTE) study. Hair and plasma data show that lopinavir, ritonavir, and efavirenz all transfer from mother to infant in utero, but only efavirenz transfers via breastfeeding. Journal of Acquired Immune Deficiency Syndromes. 2013; 63(5):578-84
Marquez C, Okiring J, Chamie G, Ruel T, Achan J, Kakuru A, Kamya M Charlebois E, Havlir D, Dorsey G. Increased Morbidity in Early Childhood Among HIV-Exposed Uninfected Children in Uganda is Associated with Breastfeeding Duration. Journal of Tropical Pediatrics. 2014 Dec;60(6):434-41.
HIV and Malaria
Kamya MR, Gasasira AF, Achan J, Mebrahtu T, Ruel T, Kekitiinwa A, Charlebois ED, Rosenthal PJ, Havlir D, Dorsey G. Effects of trimethoprim-sulfamethoxazole and insecticide-treated bednets on malaria among HIV-infected Ugandan children. AIDS. 2007; 21(15):2059-66.
Gasasira AF, Kamya MR, Achan J, Mebrahtu T, Kalyango J, Ruel T, Charlebois E, Staedke SG, Kekitiinwa A, Rosenthal P, Havlir D and Dorsey G. High risk of neutropenia in HIV-infected children following treatment with artesunate plus amodiaquine for uncomplicated malaria in Uganda. Clinical Infectious Diseases. 2008; 46:985-91.
Gasasira AF, Kamya MR, Ochong EO, Vora N, Achan J, Charlebois E, Ruel T, Kateera F, Meya DN, Havlir D, Rosenthal PJ, Dorsey G. Effect of trimethoprim-sulphamethoxazole on the risk of malaria in HIV-infected Ugandan children living in an area of widespread antifolate resistance. Malaria Journal. 2010; 9:177. PMC2903607.
Natureeba P, Kakuru A, Muhindo M, Littmann E, Ochieng T, Ategeka J, Koss CA, Plenty A, Charlebois ED, Clark TD, Nzarubara B, Nakalembe M, Cohan D, Rizzuto G, Muehlenbachs A, Ruel T, Jagannathan P, Havlir DV, Kamya MR, Dorsey G. Intermittent Preventive Treatment with Dihydroartemisinin-piperaquine for the Prevention of Malaria among HIV-infected Pregnant Women. J Infect Dis. 2017 Feb 22.
Ikilezi, G, Achan J, Kakuru A, Ruel T, Charlebois E, ClarkT, Rosenthal P; Havlir D; Kamya M; Dorsey G. Prevalence of asymptomatic parasitemia and gametocytemia among HIV-infected Ugandan children randomized to receive different antiretroviral therapies. American Journal of Tropical Medicine and Hygiene. 2013; 88(4):744-6.
Kajubi R, Huang L, Jagannathan P, Chamankhah N, Were M, Ruel T, Koss CA, Kakuru A, Mwebaza N, Kamya M, Havlir D, Dorsey G, Rosenthal PJ, Aweeka FT. Antiretroviral therapy with efavirenz accentuates pregnancy-associated reduction of dihydroartemisinin-piperaquine exposure during malaria chemoprevention. Clin Pharmacol Ther. 2017 Feb 10.
Kakuru A, Natureeba P, Muhindo MK, Clark TD, Havlir DV, Cohan D, Dorsey G, Kamya MR, Ruel T. Malaria burden in a birth cohort of HIV-exposed uninfected Ugandan infants living in a high malaria transmission setting. Malar J. 2016 Oct 18;15(1):500. PMC5070200.
Morgan M, Kumar GS, Kaiser S, Seetharam S, Ruel T. Implementation of a neonatal transcutaneous bilirubin screening programme in rural India. Paediatrics and International Child Health. 2016 Jan 6:1-5.
Kakuru A, Achan J, Muhindo M, Ikilezi G, Arinaitwe E, Mwangwa F, Ruel T, Clark T, Charlebois E, Rosenthal PJ, Havlir D, Kamya M, Tappero J, Dorsey G. Artemisinin-based Combination Therapies are Efficacious and Safe for Treatment of Uncomplicated Malaria in HIV-infected Ugandan Children. Clinical Infectious Diseases. 2014; 59(3):446-53
HIV/AIDS
Ssewanyana I , Elrefaei M, Dorsey G, Ruel T, Jones NG, Gasasira A, Kamya M, Nakiwala J, Achan J, Charlebois E, Havlir D, Cao H. Profile of T Cell Immune Responses in HIV Infected Children from Uganda. Journal of Infectious Diseases. 2007; 196:1667-1670.
Ruel T, Achan J, Gasasira AF, Charlebois ED, Mebrahtu T, Rosenthal PJ, Dorsey G, Kamya MR, Kekitiinwa A, Wong J, Havlir DV. HIV RNA suppression among HIV-infected Ugandan Children with Measles. Journal of Acquired Immune Deficiency Syndromes. 2008; 48(2):225-227.
Ssewanyana I, Baker CA, Ruel T, Bousheri S, Kamya M, Dorsey G, et al. The Distribution and Immune Profile of T Cell Subsets in HIV-Infected Children from Uganda. AIDS Research Human Retroviruses. 2009; 25(1):65-71. PMC2858297.
Ruel T, Ssewanyana I, Achan J, Gasasira A, Kamya MR, Kekitiinwa A, et al. Dynamics of T cell activation accompanying CD4 recovery in antiretroviral treated HIV-infected Ugandan children. Clinical Immunology. 2009; 131(3):410-4. PMC3032795.
Li P, Ruel T, Fujimoto K, Hatano H,Yukl S, Eller LA, Liegler T,Kamya M, Gassasira A, Dorsey G, Rosenthal Havlir DV, Wong JK. Novel application of Locked Nucleic Acid chemistry for a Taqman assay for measuring diverse human immunodeficiency virus type 1 subtypes. Journal of Virologic Methods. 2010; 170:115-20. PMC3280821
Charlebois ED, Ruel TD, Gasasira AF, Achan J, Kateera F, Akello C, Cao H, Dorsey G, Rosenthal PJ, Ssewanyana I, Kamya MR, Havlir DV. Short-term risk of HIV disease progression and death in Ugandan children not eligible for antiretroviral therapy Journal of Acquired Immune Deficiency Syndromes. 2010; 55:330-5. PMC3025136.
Boivin MJ, Ruel TD, Boal HE, Bangirana P, Cao H, Eller LA, Charlebois E, Havlir DV, Kamya MR, Achan J, Akello C, Wong JK. HIV-subtype A is associated with poorer neuropsychological performance compared with subtype D in antiretroviral therapy-naive Ugandan children. AIDS 2010; 24:1163-70. PMC2880483.
Ruel TD, Kamya MR, Li P, Pasutti W, Charlebois ED, Liegler T, Dorsey G, Rosenthal PJ, Havlir DV, Wong JK, Achan J. Early virologic failure and the development of antiretroviral drug resistance mutations in HIV-infected Ugandan children. Journal of Acquired Immune Deficiency Syndromes. 2011; 56:44-50. PMC3078046.
Ruel T, Zanoni B, Ssewanyana I, Cao H, Charlebois ED, Havlir D, Kamya MR, Feeney, M. Sex differences in HIV RNA level and CD4 percentage during childhood. Clinical Infectious Diseases. 2011; 53(6):592-599. PMC3160805.
Kay J, Wanzira H, Sandison T, Kakuru A, Bigira V, Kamya M, Homsy J, Tappero J, Havlir D, Dorsey G, Ruel T. Virologic suppression in nevirapine-exposed HIV-infected infants initiating antiretroviral therapy in rural Uganda. Journal of Tropical Pediatrics. 2012; 58(3):194-9. PMC3530275.
Ruel T, Boivin M, Boal H, Bangirana P, Charlebois E, Havlir D, Rosenthal P, Dorsey D, Achan J, Akello C, Kamya M, Wong J. Neurocognitive and motor deficits in HIV-infected Ugandan children with high CD4 cell counts. Clinical Infectious Diseases. 2012; 54(7):1001-9. PMC3297647.
Achan J, Kakuru A, Ikilezi G, Ruel T, Clark T, Charlebois E, Rosenthal P, Dorsey G, Havlir D, Kamya M. A trial of lopinavir/ritonavir-based versus non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy for the prevention of malaria in HIV-infected Ugandan children. New England Journal of Medicine. 2012; 367(22):2110-8. PMC3664297.
Ruel T, Kakuru A, Ikilezi G, Mwangwa F, Dorsey G, Rosenthal P, Charlebois E, Havlir D, Kamya M, Achan J. Virologic and immunologic outcomes of HIV-infected Ugandan children randomized to lopinavir-ritonavir or nonnucleoside-reverse-transcriptase-inhibitor therapy. Journal of Acquired Immune Deficiency Syndromes. 2014 Apr 15;65(5):535-41.
Koss CA, Natureeba P, Plenty A, Luwedde F, Mwesigwa J, Ades V, Charlebois ED, Clark TD, Achan J, Ruel T, Nzarubara B, Kamya MR, Havlir DV, Cohan D. Risk Factors for Preterm Birth Among HIV-Infected Pregnant Ugandan Women Randomized to Lopinavir/Ritonavir- or Efavirenz-Based Antiretroviral Therapy. J Acquir Immune Defic Syndr. 2014 Oct 1;67(2):128-35.
Bartlelink IH, Savic RM, Dorsey G, Ruel T, Gingrich D, Scherpbier HJ, Capparelli E, Jullien V, Young SL, Achan J, Plenty A, Charlebois E, Kamya M, Havlir D, Aweeka F. The effect of malnutrition on the pharmacokinetics and virological outcomes of lopinavir, efavirenz and nevirapine in food insecure HIV-infected children in Tororo, Uganda. Pediatric Infectious Disease Journal. 2015 Mar;34(3):e63-70.
Cohan D, Natureeba P, Koss CA, Plenty A, Luwedde F, Mwesigwa J, Ades V, Charlebois ED, Gandhi M, Clark TD, Nzarubara B, Achan J, Ruel T, Kamya MR, Havlir DV. Efficacy and safety of lopinavir/ritonavir versus efavirenz-based antiretroviral therapy in HIV-infected pregnant Ugandan women. AIDS. 2015; 29(2):183-91.
Seidman D, Ruel T, Rahangdale L, Mittal P, Pecci C, Weber S, Goldschmidt R, Cohan D, Levison J. A clinical approach to elimination of perinatal HIV transmission in resource-rich settings. Int J Gynaecol Obstet. 2015 Dec;131(3):309-10.
Koss C, Natureeba P, Nyafwono D, Plenty A, Mwesigwa J, Nzarubara B, Clark T, Ruel T, Achan J, Charlebois E, Cohan D, Kamya M, Havlir D, Young S. Brief Report: Food Insufficiency Is Associated With Lack of Sustained Viral Suppression Among HIV-Infected Pregnant and Breastfeeding Ugandan Women. J Acquir Immune Defic Syndr. 2016 Mar 1;71(3):310-5. PMC4752388.
Kadede K, Ruel T, Kabami J, Ssemmondo E, Sang N, Kwarisiima D, Bukusi E, Cohen CR, Liegler T, Clark TD, Charlebois ED, Petersen ML, Kamya MR, Havlir DV, Chamie G; SEARCH team. Increased adolescent HIV testing with a hybrid mobile strategy in Uganda and Kenya. AIDS. 2016 Sep 10;30(14):2121-6. PMC5007167.
Brown LB, Havlir DV, Ayieko J, Mwangwa F, Owaraganise A, Kwarisiima D, Jain V, Ruel T, Clark T, Chamie G, Bukusi EA, Cohen CR, Kamya MR, Petersen ML, Charlebois ED; SEARCH Collaboration. High levels of retention in care with streamlined care and universal test-and-treat in East Africa. AIDS. AIDS. 2016 Nov 28;30(18):2855-2864.
Achan J, Kakuru A, Ikilezi G, Mwangwa F, Plenty A Charlebois E, Young S, Havlir D., Kamya M. Ruel T. Growth recovery among HIV-infected children randomized to Lopinavir/ritonavir or NNRTI-based antiretroviral therapy. Pediatric Infectious Disease Journal. 2016 Dec;35(12):1329-1332. PMC5106322.
Brown LB, Ayieko J, Mwangwa F, Owaraganise A, Kwarisiima D, Jain V, Ruel T, Clark T, Black D, Chamie G, Bukusi EA, Cohen CR, Kamya MR, Petersen ML, Charlebois ED, Havlir DV. Predictors of retention in HIV care among youth (15-24) in a universal test-and-treat setting in rural Kenya. J Acquir Immune Defic Syndr. 2017 Apr 6. PMID: 28394821
Other Child Health and Health Systems
Sears D, Mpimbaza A, Kigozi R, Sserwanga A, Chang MA, Kapella BK, Yoon S, Kamya MR, Dorsey G, Ruel T. Quality of inpatient pediatric case management for four leading causes of child mortality at six government-run Ugandan hospitals. PLoS One. 2015 May 19;10(5). PMC4437786.
Salmon M, Salmon C, Benfield N, Lusi J, Masumba D, Bitwe R, Masoda M, Ruel T, Vanrooyen M. An ACCESS Guide for ICT Training on Information and Research Tools in Low Resource Settings. International Journal of Technology, Knowledge and Society. 2013. 9(1):37-50.
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Who could imagine in Africa in Congo, here, using a computer, using mobile phones to treat patients. We have learned this from Global Strategies. This is unique, in Congo, unique.
